The Birth of an Idea C Organic Germanium as Medicine
The events leading to the synthesis of an organic Germanium compound with therapeutic properties are an inspiring tale, like many scientific discoveries, involving a mixture of serendipity, intuition, persistence and faith. The figure of the now deceased Japanese researcher, Kazuhiko Asai, looms prominently in this story. For without Dr. Asai's steadfast belief and ability to persist despite great personal hardship, it is hard to imagine how organic Germanium could have made such a rapid leap from idea to actuality as a therapeutic compound.
Once something is created and exists in reality, it can be analysed, tested and perhaps improved. However, the creative process, stemming from the conception of an idea and carried through to the birth of a tangible entity, is somewhat mysterious and awe-inspiring, which often provokes in the humble person gratitude to whatever forces which inspired his insight. We owe great tribute to discoverers like Asai, who make great sacrifices and commitments to follow their curiosity to completion. The story of Dr. Asai's synthesis of the first organic Germanium compound bears at least a brief telling. His book 'Miracle Cure - Organic Germanium' is highly recommended (2).
The connection between semiconductors and organic Germanium is germane (no pun intended) to this saga, for Asai, upon reading about semiconductor properties of electrons of Germanium, pondered over the effects such a substance might have in the body.
"Germanium atomic number 32, has 32 electrons, four of which are constantly moving unsteadily along the outermost shell of the atom. These four electrons are negative electrical charge carriers and if approached by a foreign substance, one will be ejected out of its orbit. This famous phenomenon is known in electronics as the positive-hole effect which is so ingeniously utilized in forming transistors and diodes. When one of these four electrons is ejected, a positive-charge hole is created and the remaining three seize electrons from other atoms in order to maintain balance." (1)
Asai was specifically thinking about the process of dehydrogenation, and whether Germanium might be effective in removing toxic hydrogen ions from the body. More about this later.
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